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Οι γεύσεις των καπνιστών δεν τους επιτρέπουν να δοκιμάσουν πικρία του καφέ “

Οι γεύσεις των καπνιστών δεν τους επιτρέπουν να δοκιμάσουν πικρία του καφέ “

Τα τρόφιμα και τα ποτά που πωλούνται στην πανεπιστημιούπολη κατά τη διάρκεια ειδικών εκδηλώσεων μετά τις ώρες του σχολείου δεν χρειάζεται να ακολουθήσουν τις νέες οδηγίες.

  • επιτρέποντας τα κράτη και τα σχολεία που έχουν ήδη αυστηρότερες πολιτικές για να τα διατηρήσουν.
  • Το USDA λέει ότι κάνει το καλύτερό του για να βελτιώσει τα διατροφικά πρότυπα των τροφίμων που τα παιδιά τρώνε στα σχολεία, καθώς και να παρέχουν σε οικογένειες συμβουλές για το τι είναι ένα υγιεινό γεύμα. Ο Υγιεινός Παιδικός Παιδικός Πράξη του 2010 βελτίωσε σημαντικά τη διατροφική ποιότητα των σχολικών γευμάτων και αυτά τα νέα πρότυπα θα τα κάνουν ακόμη πιο υγιεινά. Μια επιλογή από φρέσκα φρούτα, σαλάτες, λαχανικά και σάντουιτς γαλοπούλας και τυριών στο γυμνάσιο της Ουάσινγκτον στο Arlington, οι άνθρωποι της Βιρτζίνια μπορούν να χρησιμοποιήσουν τους πόρους MyPlate του USDA στην ιστοσελίδα choosemyplate.gov, η οποία παρέχει συμβουλές διατροφής, υγιεινά τρόφιμα και δείγματα μενού και Συνταγές. Πέρυσι, το USDA ξεκίνησε το Πρόγραμμα Farm To School των 5 εκατομμυρίων δολαρίων, το οποίο βοήθησε τα σχολεία να έχουν πρόσβαση σε πιο υγιεινά, τοπικά τρόφιμα. Οι πολιτικές όπως αυτές θα μπορούσαν να βοηθήσουν σημαντικά τη χώρα να αντιμετωπίσει την επιδημία της παιδικής παχυσαρκίας, μία από τις κορυφαίες προτεραιότητες της κυβέρνησης του Ομπάμα. Ο David L. Katz, MD, MPH, αρχισυντάκτης της παιδικής παχυσαρκίας και διευθυντής του ερευνητικού κέντρου πρόληψης του Πανεπιστημίου Yale, έγραψε ένα συντακτικό που δημοσιεύθηκε στο περιοδικό Childhood Obesity, δηλώνοντας ότι τα σχολεία διαδραματίζουν κρίσιμο ρόλο στην ενθάρρυνση της υγιεινής διατροφής, που μπορεί Μειώστε την παχυσαρκία μεταξύ των παιδιών. Κατέληξε στο συμπέρασμα: “Τα πρότυπα για τα σχολικά τρόφιμα θα πρέπει να τεθούν υψηλά και η κοινωνία μας πρέπει να κάνει ό, τι χρειάζεται για να φτάσετε εκεί από εδώ”.

    Γράφτηκε από τον Joseph Nordqvist

    • Διατροφή / Διατροφή
    • Παχυσαρκία / απώλεια βάρους / γυμναστήριο
    • Παιδιατρική / Παιδική Υγεία
    • ul>

      Οι γεύσεις των καπνιστών «δεν τους επιτρέπουν να δοκιμάσουν πικρία του καφέ»

      Αν και η συμβατική σύζευξη έχει τσιγάρα και καφέ που πηγαίνουν μαζί, οι ερευνητές έχουν διαπιστώσει ότι οι τοξικές χημικές ουσίες στον καπνό μπορεί να παρεμποδίσουν την αναγέννηση του μπουμπούκι, με αποτέλεσμα οι καπνιστές να μην είναι σε θέση να δοκιμάσουν επαρκώς την πικρία του κανονικού φλιτζάνι του Joe.

      Οι ερευνητές, με επικεφαλής τον Nelly Jacob του Pitié-Salpêtrière Hospital APHP στη Γαλλία, δημοσίευσε τα αποτελέσματα της μελέτης τους στο περιοδικό Chemosensory Perception.

      Σημειώνουν ότι οι χημικές ουσίες του καπνού είναι ήδη γνωστό ότι προκαλούν απώλεια γεύσης στους καπνιστές, καθώς και δομικές αλλαγές στις μυκητιακές θηλές της γλώσσας – όπου βρίσκονται οι γεύσεις.

      Αυτό που ήταν άγνωστο είναι σε ποιο βαθμό επηρεάζεται το εύρος γεύσης των καπνιστών, είτε επιστρέφει στο φυσιολογικό κατά την εγκατάλειψη του καπνίσματος και αν ναι, πόσο καιρό παίρνει.

      Οι γεύσεις γεύσης είναι σε μεγάλο βαθμό υπεύθυνες για τη μεταφορά γλυκών, ξινών, πικρών, αλμυρών και μεταλλικών αισθήσεων. Σύμφωνα με τα Κέντρα Ελέγχου και Πρόληψης Νοσημάτων (CDC), οι ευθύνες του συστήματος γεύσης περιλαμβάνουν:

        Li> Ενίσχυση των συναισθημάτων της ευχαρίστησης και του κορεσμού όταν τρώτε
      • Προσδιορισμός της ποιότητας των τροφίμων και καθορίζοντας τα “καλά” γευστικά τρόφιμα από “κακά”, τα οποία θα μπορούσαν να έχουν δυνατότητες τοξίνες.

      Για να διερευνηθεί περαιτέρω οι αλλαγές στις γεύσεις που προκλήθηκαν από το κάπνισμα, ο Jacob και οι συνεργάτες του εξέτασαν την ικανότητα των 451 συμμετεχόντων στη μελέτη να αναγνωρίζουν και να είναι η ένταση των τεσσάρων βασικών προτιμήσεων – γλυκιά, ξινή, πικρή και Αλμυρός.

      Η συσσώρευση προϊόντων καπνού θα μπορούσε να εμποδίσει την αναγέννηση γεύσης

      που διαιρεί τους συμμετέχοντες σε τρεις ομάδες (καπνιστές, μη καπνιστές και πρώην καπνιστές), η ομάδα διεξήγαγε τις εθελοντικές δοκιμές κατά τη διάρκεια τριών ξεχωριστών και διαδοχικών “Παγκόσμιες ημέρες χωρίς καπνό.”

      Η ικανότητα ενός ατόμου να αναγνωρίζει αλμυρή, γλυκιά ή ξινή γούστα δεν επηρεάστηκε από την κατάσταση του καπνίσματος, λένε οι ερευνητές. Ωστόσο, η κατάσταση του καπνίσματος επηρέασε την ικανότητά τους να δοκιμάζουν την πικρία στην καφεΐνη.

      Ενώ οι πικροί υποδοχείς στη γλώσσα είναι κανονικά σε θέση να ανιχνεύσουν αυτή την αίσθηση σε ακόμη χαμηλές συγκεντρώσεις, σχεδόν το 20% των καπνιστών δεν ήταν σε θέση να εντοπίσει σωστά τη γεύση.

      των πρώην καπνιστών, το 26,5% δεν μπόρεσε να εντοπίσει τη γεύση, ενώ μόνο το 13,4% των μη καπνιστών δεν μπόρεσε να εντοπίσει σωστά τα πικρά δείγματα.

      Μιλώντας για τα ευρήματά τους, ο Jacob λέει:

      “Θεωρούμε ότι η αντίληψη της πικρής γεύσης πρέπει να εξεταστεί πιο στενά, τόσο ως εργαλείο για την παύση του καπνίσματος ή για την πρόληψη της έναρξης του καπνίσματος. Γενικότερα, θα πρέπει να αξίζει τον κόπο να εξεταστεί ο ρόλος των χημειοαισθητικών αντιλήψεων στη συμπεριφορά του καπνίσματος. ”

      Η ομάδα πιστεύει ότι η συσσώρευση ορισμένων προϊόντων καπνού στο σώμα θα μπορούσε να εμποδίσει την αναγεννητική γεύση, τα οποία θα μπορούσαν να επηρεάσουν την ικανότητα ενός ατόμου να αναγνωρίζει ορισμένες προτιμήσεις αφού εγκαταλείψουν το κάπνισμα.

      Στον κόσμο της έρευνας γεύσης, τα ιατρικά νέα σήμερα ανέφεραν πρόσφατα σε έναν ψηφιακό προσομοιωτή γεύσης που μπορεί να παράγει τα τέσσερα κύρια στοιχεία της γεύσης. Οι ερευνητές λένε ότι θα μπορούσε να χρησιμοποιηθεί κάποια μέρα για να βελτιωθεί ή να αναγεννηθεί η αίσθηση της γεύσης σε ασθενείς με καρκίνο των οποίων οι γεύσεις έχουν εξασθενήσει από τη χημειοθεραπεία.

      • Το κάπνισμα/διακοπή κάπνισμα

      Το κάπνισμα καθιστά τις γυναίκες ευάλωτες σε αιμορραγίες του εγκεφάλου, η μελέτη βρίσκει ότι οι καπνιστές-ειδικά οι θηλυκοί καπνιστές-διατρέχουν πολύ μεγαλύτερο κίνδυνο για αιμορραγία στην επένδυση του εγκεφάλου, γνωστή ως υποαραχνοειδές αιμορραγία, από τους μη καπνιστές. Αυτό είναι το συμπέρασμα μιας νέας μελέτης που δημοσιεύθηκε στο περιοδικό Stroke.

      Η υποαραχνοειδής αιμορραγία είναι μια μορφή εγκεφαλικού επεισοδίου που χαρακτηρίζεται από αιμορραγία στην περιοχή υποαραχνοειδούς του εγκεφάλου – την περιοχή μεταξύ του εγκεφάλου τους ιστούς που το καλύπτουν.

      Ενώ η υποαραχνοειδής αιμορραγία είναι σπάνια, αντιπροσωπεύοντας περίπου το 3 % όλων των εγκεφαλικών επεισοδίων, μπορεί να έχει σοβαρές συνέπειες, προκαλώντας παράλυση, κώμα και θάνατο.

      Ένας ξαφνικός, σοβαρός πονοκέφαλος είναι το κύριο σύμπτωμα της υποαραχνοειδούς αιμορραγίας και αυτό συμβαίνει συνήθως στο πίσω μέρος του κεφαλιού. Άλλα συμπτώματα περιλαμβάνουν τη μειωμένη συνείδηση και την εγρήγορση, τις αλλαγές στη διάθεση και την προσωπικότητα και την ταλαιπωρία των ματιών σε απάντηση στο φωτεινό φως.

      Η κατάσταση είναι πιο συχνή μεταξύ των γυναικών από τους άνδρες, αν και οι λόγοι για αυτό ήταν ασαφείς.

      Τώρα, ο ηγέτης της μελέτης Dr. Joni Valdemar Lindbohm, του Πανεπιστημίου του Ελσίνκι στη Φινλανδία, και οι συνάδελφοί τους λένε ότι τα ευρήματά τους δείχνουν ότι το κάπνισμα μπορεί να αυξήσει την ευπάθεια των γυναικών στην υποαραχνοειδή αιμορραγία.

      Για να φτάσουν τα ευρήματά τους, η ομάδα ανέλυσε τα δεδομένα 65.521 ενηλίκων κατά μέσο όρο ηλικίας 45 ετών που είχαν συμμετάσχει στις φινλανδικές εθνικές έρευνες, ξεκινώντας από το 1972. Περισσότεροι από τους μισούς συμμετέχοντες ήταν γυναίκες.

      Ως μέρος των ερευνών, τα θέματα ολοκλήρωσαν ορισμένα ερωτηματολόγια υγείας και φυσικές αξιολογήσεις. Συγκεκριμένα, ο Δρ Lindbohm και οι συνάδελφοί του εξέτασαν την κατάσταση του καπνίσματος των υποκειμένων και τη συχνότητα εμφάνισης υποαραχνοειδούς αιμορραγίας.

      Οι συμμετέχοντες παρακολουθήθηκαν κατά μέσο όρο 21 χρόνια από τη βασική γραμμή μελέτης. Η παρακολούθηση συνεχίστηκε μέχρι τις 31 Δεκεμβρίου 2011, ή έως ότου τα άτομα είχαν το πρώτο εγκεφαλικό επεισόδιο τους ή πέθαναν.

      Οι θηλυκοί καπνιστές έχουν οκτώ φορές μεγαλύτερο υποαραχνοειδές κίνδυνο αιμορραγίας

      σε σύγκριση με τους μη καπνιστές, οι ερευνητές διαπίστωσαν ότι οι καπνιστές ήταν πιο πιθανό να βιώσουν μια υποαραχνοειδή αιμορραγία. Όσο περισσότερα τσιγάρα καπνίζουν καθημερινά, τόσο υψηλότερο είναι ο κίνδυνος τους και οι γυναίκες έμειναν χειρότερα από τους άνδρες.

      Μεταξύ ελαφρών καπνιστών-που ορίζονται ως κάπνισμα 1-10 τσιγάρα καθημερινά-οι άνδρες ήταν 1,93 φορές πιο πιθανό να έχουν υποαραχνοειδή αιμορραγία από τους μη καπνιστές, ενώ οι γυναίκες ήταν σε 2,95 φορές μεγαλύτερο κίνδυνο.

      Μεταξύ εκείνων που καπνίζουν 11-20 τσιγάρα την ημέρα, οι άνδρες ήταν 2,13 φορές πιο πιθανό να έχουν υποαραχνοειδή αιμορραγία από τους μη καπνιστές, ενώ ο κίνδυνος ήταν 3,89 φορές μεγαλύτερος για τις γυναίκες.

      Οι γυναίκες που καπνίζουν 21-30 τσιγάρα την ημέρα ήταν 8,35 φορές πιο πιθανό να βιώσουν μια υποαραχνοειδή αιμορραγία από τους μη καπνιστές, ενώ οι άνδρες που καπνίζουν 21-30 τσιγάρα καθημερινά ήταν 2,76 φορές μεγαλύτερος κίνδυνος.

      Αυτά τα αποτελέσματα, λένε οι συγγραφείς, μπορεί να βοηθήσουν να εξηγήσουν γιατί η υποαραχνοειδής αιμορραγία είναι πιο συνηθισμένη στις γυναίκες από τους άνδρες.

      “Το γυναικείο φύλο έχει περιγραφεί ως ανεξάρτητος παράγοντας κινδύνου για την υποαραχνοειδή αιμορραγία, αλλά διαπιστώσαμε ισχυρές ενδείξεις ότι ο αυξημένος κίνδυνος στις γυναίκες εξηγείται από την ευπάθεια του καπνίσματος.

      Τα αποτελέσματά μας υποδεικνύουν ότι οι παράγοντες κινδύνου ηλικίας, φύλου και τρόπου ζωής διαδραματίζουν κρίσιμο ρόλο στην πρόβλεψη ποιοι ασθενείς κινδυνεύουν για υποαραχνοειδή αιμορραγία και υπογραμμίζουν τη σημασία των αποτελεσματικών στρατηγικών διακοπής του καπνίσματος “.

      Ο Δρ Joni Valdemar Lindbohm

      η εγκατάλειψη του καπνίσματος μπορεί να μειώσει τον κίνδυνο υποαραχνοειδούς αιμορραγίας

      Αλλά δεν είναι όλα κακά νέα. Οι ερευνητές διαπίστωσαν ότι η διακοπή του καπνίσματος μπορεί να μειώσει σημαντικά τον κίνδυνο υποαραχνοειδούς αιμορραγίας.

      Τα αποτελέσματα της ανάλυσης αποκάλυψαν ότι οι άνδρες και οι γυναίκες που δεν είχαν καπνίσει για τουλάχιστον 6 μήνες είχαν κίνδυνο υποαραχνοειδούς αιμορραγίας που ήταν συγκρίσιμη με τους μη καπνιστές.

      “Δεν υπάρχει ασφαλές επίπεδο καπνίσματος”, τονίζει ο Δρ Lindbohm. “Φυσικά η καλύτερη επιλογή δεν είναι ποτέ να ξεκινήσετε. Ωστόσο, η εγκατάλειψη του καπνίσματος μπορεί να μειώσει τον κίνδυνο υποαραχνοειδούς αιμορραγίας και στα δύο φύλα. ”

      Οι συγγραφείς παραδέχονται ότι υπάρχουν ορισμένοι περιορισμοί στη μελέτη τους. Για παράδειγμα, επισημαίνουν ότι η πρόσληψη αλκοόλ των υποκειμένων, η χρήση φαρμάκων για την αρτηριακή πίεση ή η συχνότητα εμφάνισης υψηλής χοληστερόλης θα μπορούσε να επηρεάσει τα αποτελέσματα.

      Ακόμα πιστεύουν ότι τα ευρήματά τους υπογραμμίζουν τη σημασία της διακοπής του καπνίσματος προκειμένου να μειωθούν οι πιθανότητες μιας πιθανής απειλητικής για τη ζωή κατάσταση.

      Μάθετε πώς ο εμμηνορροϊκός κύκλος θα μπορούσε να βοηθήσει τις γυναίκες να σταματήσουν το κάπνισμα.

      • Νευρολογία/νευροεπιστήμη
      • Κάπνισμα/διακοπή κάπνισμα
      • Γυναικεία υγεία/γυναικολογία

      Το κάπνισμα μπορεί να επηρεάσει το DNA για περισσότερα από 30 χρόνια

      Το κάπνισμα επηρεάζει το ανθρώπινο γονιδίωμα – ένα πλήρες σύνολο DNA σε ένα άτομο, συμπεριλαμβανομένων όλων των γονιδίων – με τη μορφή μεθυλίωσης DNA, βρίσκει μια νέα μελέτη που δημοσιεύτηκε Σε μια κυκλοφορία περιοδικών American Heart Association: Καρδιαγγειακή γενετική. Ορισμένες θέσεις μεθυλίωσης DNA έχουν βρεθεί ότι επιμένουν ακόμη και μετά από 30 χρόνια διακοπής.

      Η μεθυλίωση του DNA είναι μια διαδικασία με την οποία τα κύτταρα ελέγχουν τη δραστικότητα του γονιδίου και συχνά τροποποιεί τη λειτουργία των γονιδίων. Οι επιστήμονες έχουν διαπιστώσει ότι η μεθυλίωση του DNA θα μπορούσε να αποκαλύψει την ιστορία του καπνίσματος ενός ατόμου και ως εκ τούτου θα μπορούσε να αναπτύξει στοχοθετημένες νέες θεραπείες για ασθένειες που σχετίζονται με το κάπνισμα.

      “Αυτά τα αποτελέσματα είναι σημαντικά επειδή η μεθυλίωση, ως ένας από τους μηχανισμούς της ρύθμισης της γονιδιακής έκφρασης, επηρεάζει τα γονίδια που είναι ενεργοποιημένα, τα οποία έχουν επιπτώσεις στην ανάπτυξη ασθενειών που σχετίζονται με το κάπνισμα”, λέει ο Dr. Stephanie J. Λονδίνο, τελευταίος συγγραφέας και αναπληρωτής αρχηγός του υποκαταστήματος επιδημιολογίας στο Εθνικό Ινστιτούτο Περιβαλλοντικών Επιστημών Υγείας – μέρος των Εθνικών Ινστιτούτων Υγείας.

      Εξίσου σημαντικό είναι το εύρημα μας ότι ακόμα και μετά από κάποιον που σταματά το κάπνισμα, εξακολουθούμε να βλέπουμε τα αποτελέσματα του καπνίσματος στο DNA τους “, προσθέτει.

      Το κάπνισμα τσιγάρων είναι ένας σημαντικός τροποποιητής της μεθυλίωσης του DNA. Η έρευνα έχει αποκαλύψει γονίδια που σχετίζονται με το κάπνισμα που συμβάλλουν στην ανάπτυξη ασθενειών που σχετίζονται με το κάπνισμα. Η μεθυλίωση του DNA είναι επίσης ένας πιθανός σύνδεσμος μεταξύ του καπνίσματος και του καρκίνου, καθώς και της προγεννητικής έκθεσης καπνού τσιγάρων και της ανάπτυξης χρόνιων ασθενειών σε ενήλικες.

      Εκτιμάται ότι 40 εκατομμύρια ενήλικες στις Ηνωμένες Πολιτείες καπνίζουν σήμερα τσιγάρα. Το κάπνισμα των τσιγάρων θεωρείται ως η κύρια αιτία της ασθένειας και του θανάτου που μπορεί να προληφθεί από το Ηνωμένο Βασίλειο, που αντιπροσωπεύει περισσότερους από 480.000 θανάτους κάθε χρόνο. Περισσότεροι από 16 εκατομμύρια Αμερικανοί ζουν με ασθένεια που σχετίζεται με το κάπνισμα.

      Παρά τα ποσοστά καπνίσματος που μειώνονται σε πολλές χώρες παγκοσμίως ως αποτέλεσμα των εκστρατειών καπνίσματος και της νομοθετικής δράσης, ακόμη και δεκαετίες μετά την εγκατάλειψη των ανθρώπων, οι πρώην καπνιστές διατρέχουν μακροπρόθεσμο κίνδυνο ασθενειών που περιλαμβάνουν ορισμένους καρκίνους, χρόνια αποφρακτική πνευμονική νόσο και εγκεφαλικό επεισόδιο.

      Οι μοριακοί μηχανισμοί πίσω από αυτές τις μακροπρόθεσμες επιδράσεις είναι ασαφείς. Ωστόσο, προηγούμενη έρευνα έχει συνδέσει θέσεις μεθυλίωσης DNA με γονίδια που συνδέονται με στεφανιαία καρδιακή νόσο και πνευμονική νόσο, γεγονός που υποδηλώνει ότι η μεθυλίωση του DNA μπορεί να διαδραματίσει κάποιο ρόλο.

      Οι ερευνητές ανέλυσαν δείγματα αίματος από σχεδόν 16.000 συμμετέχοντες από 16 ομάδες που συμπεριλήφθηκαν στις ομάδες για την καρδιά της καρδιάς και της γήρανσης στη Γενετική Επιδημιολογία (Charge), συμπεριλαμβανομένης μιας ομάδας από τη μελέτη Framingham Heart που ακολούθησαν οι ερευνητές από τότε 1971.

      Κοινές θέσεις μεθυλίωσης που συνδέονται με καρδιαγγειακές παθήσεις, καρκίνες

      σε σύγκριση με τους μη καπνιστές δια βίου, η ομάδα διαπίστωσε ότι οι θέσεις μεθυλίωσης DNA που σχετίζονται με το κάπνισμα συνδέονταν με περισσότερα από 7.000 γονίδια – Το ένα τρίτο των γνωστών ανθρώπινων γονιδίων.

      Τα ευρήματα υποδηλώνουν ότι η πλειονότητα των θέσεων μεθυλίωσης του DNA σε πρώην καπνιστές επέστρεψε σε επίπεδα που παρατηρήθηκαν σε ποτέ καπνιστές εντός 5 ετών από την παύση του καπνίσματος. Ωστόσο, ορισμένες θέσεις μεθυλίωσης DNA παρέμειναν ακόμη και 30 χρόνια μετά τη διακοπή του καπνίσματος.

      Οι πιο συνηθισμένες θέσεις μεθυλίωσης ϋΝΑ που ανιχνεύθηκαν συνδέονταν με γονίδια που σχετίζονται με μεγαλύτερο κίνδυνο ασθενειών που σχετίζονται με το κάπνισμα, όπως καρδιαγγειακές παθήσεις και ορισμένοι καρκίνοι.

      Οι ερευνητές δείχνουν ότι οι μακροπρόθεσμες θέσεις μεθυλίωσης DNA μπορούν να δώσουν έμφαση στα γονίδια που θα μπορούσαν να βάλουν τους πρώην καπνιστές σε κίνδυνο να αναπτύξουν ορισμένες ασθένειες, ακόμη και δεκαετίες μετά την εγκατάλειψη. Αυτή η ανακάλυψη θα μπορούσε να οδηγήσει σε ερευνητές που αναπτύσσουν βιοδείκτες για την αξιολόγηση του ιστορικού του καπνίσματος, γεγονός που μπορεί να οδηγήσει σε νέες θεραπείες που θα μπορούσαν να στοχεύσουν ενδεχομένως στις θέσεις μεθυλίωσης.

      “Η μελέτη μας έχει βρει επιτακτικές αποδείξεις ότι το κάπνισμα έχει μακροχρόνια επίδραση στα μοριακά μας μηχανήματα, μια επίδραση που μπορεί να διαρκέσει περισσότερο από 30 χρόνια”.

      Roby Joehanes, Ph.D., Harvard Medical School , που σημαίνει ότι το σώμα σας προσπαθεί να θεραπευτεί για τις επιβλαβείς επιπτώσεις του καπνίσματος του καπνού “, καταλήγει ο Joehanes.

      Διαβάστε για το πώς το κάπνισμα πυκνώνει τον τοίχο της καρδιάς και μειώνει την ικανότητα της καρδιάς να αντλήσει αποτελεσματικά.

      • Καρκίνος/Ογκολογία
      • Καρδιαγγειακή/Καρδιολογία
      • Κάπνισμα/Καπνίστε το κάπνισμα

      Το κάπνισμα πυκνώνει τους τοίχους της καρδιάς και μειώνει τη λειτουργία

      Υπάρχουν ήδη πολλοί λόγοι για να σταματήσουν το κάπνισμα, αλλά μια μελέτη που δημοσιεύθηκε αυτή την εβδομάδα παρέχει ακόμα. Σύμφωνα με τα αποτελέσματα, που δημοσιεύθηκε στην κυκλοφορία του περιοδικού: καρδιαγγειακή απεικόνιση, το κάπνισμα πυκνώνει τον τοίχο της καρδιάς, μειώνοντας την ικανότητα άντλησης.

      Το κάπνισμα είναι μια σημαντική αιτία καρδιαγγειακής νόσου.

      έχει διαπιστωθεί ότι ο καπνός του καπνίσματος οδηγεί σε αυξημένο κίνδυνο καρδιακής ανεπάρκειας, ακόμη και σε άτομα χωρίς καρδιαγγειακές παθήσεις.

      Ωστόσο, ο μηχανισμός με τον οποίο ο καπνός βλάπτει την καρδιά και προκαλεί καρδιαγγειακά συμβάντα δεν έχει βρεθεί.

      Μελέτες απεικόνισης που εξετάζουν τις αλλαγές στη δομή της καρδιάς που σχετίζονται με το κάπνισμα έχουν πραγματοποιηθεί. Ωστόσο, μέχρι σήμερα, τα αποτελέσματα ήταν αντιφατικά.

      Ορισμένοι ερευνητές έχουν βρει μια σχέση με την αύξηση της μάζας της αριστερής κοιλίας της καρδιάς. Άλλοι δεν βρήκαν καμία αλλαγή και άλλοι εξακολουθούν να βρήκαν μείωση της μάζας.

      Η σημασία της αριστερής κοιλίας

      Η αριστερή κοιλία έχει ιδιαίτερο ενδιαφέρον για τους ερευνητές του καπνού επειδή είναι ένας ζωτικός παίκτης στο σύστημα άντλησης της καρδιάς. Το τοίχωμα της αριστερής κοιλίας είναι κυρίως κατασκευασμένο από μυς, έτσι, όπως και κάθε μυς, αυξάνεται σε μέγεθος σε απόκριση της εργασίας σκληρότερα.

      Ορισμένοι παράγοντες υγείας μπορούν να αυξήσουν τον φόρτο εργασίας της καρδιάς και, κατά συνέπεια, το πάχος του τοιχώματος της αριστερής κοιλίας (υπερτροφία της αριστερής κοιλίας). Αυτοί οι παράγοντες περιλαμβάνουν κάποιες καρδιακές παθήσεις και υψηλή αρτηριακή πίεση.

      Η υπερτροφία της αριστερής κοιλίας είναι γνωστό ότι οδηγεί σε απώλεια καρδιακής λειτουργίας, η οποία μπορεί να οδηγήσει σε επιπλοκές που περιλαμβάνουν διακοπή στην παροχή αίματος της καρδιάς, της αρρυθμίας και του εγκεφαλικού επεισοδίου.

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          Judi Online Langkah untuk menuju ahli disaat bermain judi ulung

          Banyak penggemar Judi Online dalam hal ini bingung yaitu permainan judi itulah. Kali ini pribadi akan membagikan Tips akan menjadi hebat dalam bermain profesional. Jadi ahli pada saat bermain judi kompeten adalah niat setiap kamu yang turut serta dalam pasangan. Namun jika suka menang saat bermain judi tak dapat hanya menitipkan keberuntungan kepada, melainkan wajib mengetahui taktik dan anggaran yang awas. Jadi hendaknya pemain bertaruh casino ini scam, sebaiknya evaluasi karangan berikut ini.

          Dalam artikel di bawah ini, kami memiliki kemampuan berbagi yang Anda begitu banyak pengalaman jenis pasangan yang yang berhasil yang pastinya telah diperoleh para petaruh profesional dikala periode kaderisasi keterampilan bersama permainan sampai terampil.

          Judi online terbaik membutuhkan rumus dan pikiran yang akil. Pengalaman mainlah yang tetap menang bocor yang perlu diingat pecinta:

          Penjudi ahli dengan kemungkinan menang yang tinggi, banyak sekali hingga puluhan kemenangan, selain mereka dengan mengandalkan kelebihan mereka. Terkait adalah penjelasan yang pasti salah. Amat benar selama bermain judi, https://sipil.ub.ac.id/assets/css/ kemujuran tidak bisa mengacuhkan pemain, tidak disangka bukan berguna mereka tak memiliki perhitungan.

          Demi menjadi fans profesional, pemain harus lewat periode pemelajaran yang antusias, menggambar kemahiran dan manual mereka swasembada yang kurang terlupakan, jadinya terus-menerus minta pengalaman tepat melalui pemain yang bertaruh, pertempuran, selanjutnya secara terkontrol merujuk bagi pertempuran terbaik, bersama dengan penelaahan. cara memikirkan dan membuat strategi yang akan cermat biasanya membawa kinerja nantinya.

          Kemampuan Judi Online untuk berharga

          Kekuatan

          Ini tidak lain tidak bukan iallah salah satu memang harus didapat untuk berjaya dalam bisnis apa hanya dan pemain yang bertaruh tidak lain. Bukannya Pemain tidak akan berhasil semudah membayangkan tangan ketika menjadi anda profesional. Dengan perlu Penjudi lakukan bisa jadi bertahan pada saat belajar dan juga menggambar jam terbang berharga setiap harinya.

          Memiliki mental keingintahuan sehingga rasa ingin tahu:Hanya bagi yang memiliki asi untuk nyantri serta suka belajar, menentukan pada lisensi, Pelajari kepandaian bermain judi poker melalui taruhan, akan menonolong Anda menulis meng-abadikan hal-hal di perlu rasakan dan tahap untuk bersekolah. Untuk menjadi juara, kesalahan seharusnya diminimalkan, jadinya bahwa Pemain dapat membantu teknologi permainan yang elok untuk dirinya sendiri.

          Perhatikan baik-baik saat bermain

          Setiap harinya, Anda harus sampai teratur mengamati situasi yaitu cermat, mencari tahu kemajuan dengan tekanan beserta ekspresi lawan-lawan untuk sanggup membeli panduan menuju hasil baik.

          Berolahraga via teratur

          Via teratur belajar dan mempelajari cara teknik pemasangan sendiri karena rajin berguna Anda mengarahkan keterampilan yang Anda perlukan. Selain itu, berkat latihan memang teratur, Kalian akan memperluas kemampuan beranggapan, menalar pikiran dan biasanya sukses di masa depan.

          Berlatihlah itu teratur atau tekun

          Benar-benar percaya tenang di ketahui tegas

          Positif menang / kalah, Player juga diharuskan menjaga peristiwa pikiran menjadi selalu enjoy, agar pergi mengarah bagi situasi akan ke tidak tertata, membuat awak Anda cemas dan kemudian mengambil keputusan akan ke tidak cermat. Selain itu, Orang-orang juga pastikan anda memiliki niat, jangan ragu saat bermain kartu. Walaupun demikian, bukan bersuara Anda usahakan jangan berpikir benyek sebelum mengambil kesimpulan.

          Beberapa arahan kecil yang akan perlu diingat dalam strategi judi

          Saat bermain judi online terpercaya, untuk win, pemain penting untuk memiliki tips dan kiat sendiri, di meliputi informasi penting di bawah:

          Berikan metode yang masuk akal tergantung buat situasinya

          Melakukan taktik yang beda tergantung selama bermain situasinya ingin membantu Player mengatasi soal dalam permainan, memuat Anda prediksi menang yang mana lebih baik.

          Bagi yang telah melaksanakan strategi pada waktu dengan relatif boyak tetapi bukan efektif, Pastikan anda belajar dari pengalaman tentu mengubah trik, atau sudahi berjudi untuk mengamati dan memperingati di yang mana masalahnya. Tidak diperbolehkan marah lalu terikat, alkisah Anda atau kehilangan ada banyak lagi.

          Dipahami peluang untung dan tidak mungkin unggul dalam permainan poker online

          Untuk berdiri sebagai pemain guna sukses, kalian profesional secepatnya mengetahui ramalan memenangkan taruhan yang player ikuti.

          Akan ada permainan sama tingkat hadiah yang tambahan tinggi dibandingkan yang lain, dan dari posisi ke sewaktu akan ada banyak sekali atau lebih tidak banyak peluang bagi menang,…..

          Pengurusan modal

          Pisahkan para penjudi, organisasi modal yang akrab dan betul akan mendukung mereka memahami cara bermain sampai wajar bersama bijaksana. Mata uang mempengaruhi kepastian pemain, rencana serta kejiwaaan saat bermain.

          berhenti pada waktu sampai tepat

          Pada kenyataannya, banyak orang anjlok karena betting, karena tidak tahu kapan saatnya berhenti. Pastikan anda memiliki pendekatan khusus di dalam judi, menjalankan tujuan dengan arah taruhan, tahu dimana harus stop.

          Pemain mesti mengetahui vlek berhenti akan ke benar

          Secara perhitungan, pecinta harus memagari bermain begitu mereka mau memenangkan dua, 5 waktu modal dia, atau dalam mereka kelonggaran hingga 70% dari investasi awal yaitu mereka.

          Jadilah pemain akan ke cerdas berserta tetap terkejut adalah pengetahuan perjudian hasil positif terbaik guna harus diingat oleh para bettor profesional.

          Agar berpartisipasi dalam permainan Judi Online guna menarik, Player tersebut dapat datang kepada alamat platform web: Agensports untuk mempublikasikan akun. Salut bermain dan sukses!

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            To je poput mama + tata kako vam čita priču prije spavanja!

            To je poput mama + tata kako vam čita priču prije spavanja!

            i kasnije: dvoboj.

            Imali smo ostatke planirane za večeru. Svakome je vlastiti!

            Evo što smo bili naoružani:

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            dvije pane (Er, jedan, jedan lonac )

            riža, grašak + grah za mene

            proso, crni grah, kukuruz, mrkva za njega.

            Oboje su umiješali jaja i sir na vrhu. Provjerite Mattov sir!

            Mine je završio s kozjim sirom i Dougovim orasima na vrhu! (more…)

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              Cara Tembus Judi Berjudi Slot Online

              Ciri khas menang berjudi main slot online, https://sipil.ub.ac.id/assets/css/ jika Anda misalnya pemain permainan yang senang mencari duit dengan enteng di mari. Kami berhasil membagikan salah satu Tips Ciri Menang Judi Slot, Mesin judi slot sendiri salah satu pilihan bandar yang teramat tepat akan anda seharusnya mendapatkan jackpot yang tanpa batas karena gim yang akan orang tersebut mainkan mengenai bergantung di keberuntungan bettor.

              Namun bukan hanya sekedar profit saja disarankan ada sedikit cara dalam bisa win permainan ini dan saat sudah mengenal caranya tidak hanya tidak mungkin bila jackpot atau lebih sederhana saja didapatkan tentunya.

              Cara Mendapatkan kemenangan Judi Berjudi Slot Online sampai Langkah-langkahnya

              Waktu bermain judi slot Roulette Ini tentunya banyak yang berharap kemenangan ada melalui pihak seluruh pemainnya, biarpun tidak di dapati cara untuk mengalahkan hoki untuk namun rahasia ini sanggup memberikan kamu untuk mengecilkan kekalahan pada waktu bermain jika saat ini enggak beruntung, selanjutnya ini tips yang akan kami mengoper semoga memperoleh anda luangkan pada saat jenis permainan nanti.

              Andalkan Pay Line yang Pintar

              Kemenangan maksimal yang akan master judi dapatkan sejak permainan judi slot sendiri apabila dari asosiasi gambar dalam hal ini didapat persis dan berbunyi dengan kesatuan mercenaries yang mana telah berasal. Jika anda join judi slot tradisional maka kemungkinan pembayarannya cukup dengan dalam suatu baris jua, namun jika player tersebut bermain slot online maka marak pembayaran serta garis yang lainnya dengan bangun pay line slot online kebanyakan 9, 15, 25, 50 dan boleh lebih lagi.

              Kompensasi biasanya dibayarkan ketika garisnya seperti yang akan sudah diseting bisa Diagonal, Horizontal atau Vertikal. Orang-orang judi semestinya lebih telik melihat bintik dimana para penjudi ingin memainkan dan terus-terusan memperhatikan kehati-hatian karena bisa sulit potong garis tentu saja mendapatkan kemenangan memang besar. Jika Anda berhasil mencapai garis yang telah di pilih maka Kalaian akan menguasai banyak uang lalu koin dibayarkan ke nominal di rekening Anda beberapa diantara dapat menyimpan dana ingin digunakan selanjutnya untuk bermain.

              Pasang taruhan Dengan Tataan Anda Milik pribadi

              Setiap player yang betting mesin slot online atau judi online di sbobet dingdong pasti memiliki cara bermain yang bervariasi karena bagaimana gaya kejuaraan para pemain yang di maksud bisa menjadi juara sejumlah hadiah, sebagian orang berasumsi bahwa opsi mesin tiba-tiba faktor yang terbesar kemenangan bila bermain judi slot. permainan judi slot itu sendiri, walaupun begitu ada juga untuk mengatakan lalu mesin enggak bergantung untuk kemenangan tetapi cara ketukan yang bopong kemenangan tersebut. Banyak arus orang memainkan ini dan ada para fitur untung seperti Cuma-cuma Spin dan juga melakukan gulungan double terhadap garis untuk telah muncul, jika pastikan anda mendapatkan yang begini maka dipastikan Anda atau berhasil berjudi ini.

              Tidak Memilih Instrumen Dengan Hadiah Yang Luar biasa

              Pasti kau bingung mengapa kami merekomendasi anda dalam tidak menentukan mesin slot dengan keuntungan sebesar poker online, sudah secara umum mesin keberhasilan yang melimpah akan krisis dicari indungnya. Pilih alat dengan keuntungan kecil disebabkan jackpotnya gampang berarti kebanyakan terkena keberhasilan. Dan jangan lupa untuk terus-menerus memperhatikan pemisah kredit kompetisi di Judi Slot Bar/Arcade yang akan player tersebut mainkan mudah – mudahan dapat memenangkan jackpot serta mudah.

              Memilih Bandar Memasang Slot Online Recommended

              Bandar atapun Dealer memproduksi sebuah jalan yang pastikan anda anda observasi sebelum melakukan pertaruhan pada. Dengan bermain di agen maupun bandar slot online terpercaya patut dapat dipastikan kalau anda taruhan disalah 1 agen sudah terpercaya tersebut beberapa jumlah hasil baik yang mereka dapatkan saat bermain judi slot akan dibayar. Maka dari itu pasti dipastikan player telah menentukan bandar unggulan sehingga setiap kali anda bermain anda jangan khawatir jadinya merasa adem selama bermain judi slot.

              Demikian masukan dari diri Cara Memenangi Judi Slot Judi togel yang bisa tujuan gunakan saat bertaruh judi slot judi togel pastinya. Bahwa masih tak paham cara memainkannya maka dari itu ada baiknya player coba guna membaca siasat yang abdi berikan ulang. Setelah anda tekun memahami tanda yang saya berikan untuk anda setelah itu tidak ada salahnya terhadap mencoba menggunakannya dengan memilih judi slot. Lulus mencoba maka semoga Pemain beruntung.

              Es Css Modules

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                Rengeteg élelmiszer -erőforrás van körülöttünk a rendelkezésünkre.

                Rengeteg élelmiszer -erőforrás van körülöttünk a rendelkezésünkre.

                A színek világosabbnak tűnnek, és a zöldségek „sértetlenebbnek” tűnnek, ami arra készteti, hogy azt higgyem, hogy a tápanyagok megőrzése nagyobb lehet. Még több mint 20 éves nyomás főzés után is csodálkozom, hogy milyen élénk színű sárgarépa van, amikor ilyen módon főztek. Ez a munka nagyon jól főz egy azonnali edényben? hüvelyesek. Szeretem, hogy a csicseriborsó miként alakul ki az azonnali edényben. Továbbá, ha az azonnali edényük megvan, akkor az emberek saját joghurtot készíthetnek, ha a fazékot inkubátorként használják. (more…)

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                      The bookmaker has diversified betting price methods by which Indian users can withdraw their funds from their accounts. As you’ll have the ability to see, the number of bets on sports activities here is just huge. And that’s not all, because the service offers to bet on the finish result of the match, on a selected participant, on the total rating, on the account of a selected team, and so on. Every participant who’s into betting has had the thought, “What if I want to bet outside of simply my home? ” You can wager wherever you are, using a state-of-the-art cellular consumer. But earlier than downloading, allow apps from third-party sources to be installed.

                      These players often are available through a referral hyperlink offered to them by 1xbet affiliate program promoters. Affiliate program promoters earn cash from commissions generated when their referrals register with their direct hyperlink or promo code.

                      Race followers face a nice range of markets for horse and greyhound racing as properly. The cell app works with various currencies and accepts over one hundred ten payment strategies to fulfill the individual banking needs of all customers. As the web site just isn’t sensible and some individuals choose the app for various causes, a devoted app has been put online. Already very fashionable, it’s not as accessible as the opposite apps we’re used to downloading.

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                      Store your new password in 1Password so you presumably can fill it from any system. 1XBet will allow you to to foretell the outcome of the match and in addition train you tips on how to guess techniques to get most outcomes. 1xBet app can be free to download and use, which is a big benefit. 1xBet is like an funding platform compared with different bookmakers. Bitcoin seems to be back on a bull run after US watchdogs and Circle issued statements on USDC causing restored investor confidence in markets. BudBlockz, a decentralized on-line platform, is disrupting the global hashish market with their farms, dispensaries, and NFT project, Ganja Guruz.

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                      The betting markets are easy to navigate, and we loved the pace of withdrawals. The app is easy to make use of and navigate, and there’s no trouble with the registration and betting course of. Go to the safety settings of your system and allow the installation of files from unknown sources. Bettingguide is your complete guide to gambling, betting and online casino in India. Naturally, those who wish to win cash by betting on the app must deposit actual funds.

                      Despite its concentrate on the CIS area, the corporate has a stable presence in different main markets with few exceptions. One of the few downsides of the sportsbook is that it prohibits registrations from the US and Great Britain.

                      It is free in the Netherlands, so do not forget to alter your region within the settings. What I really endure from is the dearth of reside broadcasts, it’s truly entertaining to observe them after you’ve got скачать 1хбет приложение на андроид made few good stakes.

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                      As of January 2023, 1xBet not seems to be located in Curaçao after being declared bankrupt, following a lawsuit towards the company and its licensor. The website continues to operate on-line, and has since relocated to Nigeria. (also generally known as “1xBet”) is an online playing firm licensed by Curaçao eGaming License. In 2019, they skilled considerable progress, briefly sponsoring Chelsea FC and Liverpool FC earlier than being ousted for his or her involvement in illegal actions. This permits using your social media credentials to access your 1xBet cell account in case you neglect your username and password. It’s not so complicated to addContent it to “The Apple” – the newest contemporary model is on the market on 1xbet web site.

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